Chromosome Studies in Normal and Leukemic Rats
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چکیده
ECENTLY DEVELOPED technics for the study of chromosomes in peripheral blood and bone marrow cells have resulted in important discoveries in the field of cytogenetics. Recognition of numerical and morphologic changes following irradiation and the identification of a characteristic defect, the Ph’ chromosome, in human chronic myelogenous leukemia ( CML) have aroused speculation on the relationship of chromosome abnormalities tQt me mechanism of leukemogenesis. J-.& a part of a long-term program of research on the induction of myelogenous leukemia in the rat, cytogenetic studies were carried out on normal, irradiated and three methylcholanthrene (3MCA ) treated rats, as well as on a small series of animals with induced leukemia 7
منابع مشابه
Chromosome Studies in Normal and Leukemic Rats.
ECENTLY DEVELOPED technics for the study of chromosomes in peripheral blood and bone marrow cells have resulted in important discoveries in the field of cytogenetics. Recognition of numerical and morphologic changes following irradiation and the identification of a characteristic defect, the Ph’ chromosome, in human chronic myelogenous leukemia ( CML) have aroused speculation on the relationshi...
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